Efficacy and Safety of Tenofovir Disoproxil Fumarate in Preventing Vertical Transmission of Hepatitis B in Pegnancies with High Viral Load
The available evidence suggests that TDF is effective and safe in preventing vertical transmission of hepatitis B in pregnancies exhibiting a high viral load.
The Efficacy and Safety of Tenofovir in The Prevention of Hepatitis B Virus Recurrence Following Liver Transplantation
The results of this study, after a 36-month follow-up period, were encouraging and demonstrated that TDF therapy is safe and efficacious in treating HBV-positive organ transplant patients.
Significance of definitions of relapse after discontinuation of oral antivirals in HBeAg-negativechronic hepatitis B
The aim of this study was to assess the impact of different definitions on the rates of post-treatment relapse and therefore on the probability of retreatment in such patients who discontinued effective long-term NAs therapy.
The Definition of Relapse
Trajectories of serum hepatitis B surface antigen kinetics in patients with chronic hepatitis Breceiving long-term nucleos(t)ide analogue therapy
We investigated the patterns of serum HBsAg kinetics and their association with therapeutic outcomes in genotype B- or C-infected CHB patients receiving long-term NA therapy.
Chronic Hepatitis B
Serum HBsAg Levels
Predictors of Early Readmission in Patients With Cirrhosis After the Resolution of Bacterial Infections
CRP showed to be a strong predictor of early hospital readmission and 6-month mortality in patients with cirrhosis after hospitalization for bacterial and/or fungal infection.
Bacterial And/Or Fungal Infection
Hepatitis B virus pregenomic RNA in hepatocellular carcinoma:A nosological and prognosticdeterminant
HCC replicating HBV represents a subtype of weakly invasive HCC with a transcriptomic signature.
Long-term response after stopping tenofovir disoproxil fumarate in non-cirrhotic HBeAg-negative patients - FINITE study
This study investigated the potential to discontinue tenofovir disoproxil fumarate (TDF) therapy in HBeAg-negative patients.
Discontinue TDF Therapy
Fine-Tuning Hepatitis B Treatment Strategies（2）
Gao and colleagues evaluated the effect of antiviral therapy on the incidence of HCC in patients with cirrhosis with lower HBV DNA levels.
HBV DNA Load
Fine-Tuning Hepatitis B Treatment Strategies（1）
Early diagnosis of HBV through effective screening programs allows timely initiation of therapy to prevent disease progression and decompensation.
Chronic Hepatitis B
Systematic review with meta-analysis the efficacy and safety of tenofovir to prevent mother-to-child transmission of hepatitis B virus
The pooled results from comparative trials (599 pregnancies) showed that tenofovir significantly reduced the risk of infant hepatitis B surface antigen seropositivity by 77% .
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